Normal functioning of organisms is influenced by their environment, most life forms survive and function efficiently despite fluctuations in the environment. Animals have a remarkable property to withstand challenges from the external environment such as variations in the availability of nutrients, which is the main source of energy for various physiological needs. In most cases organisms cope well during such challenges, which they owe to various adaptive responses that aid in maintaining a stable interior milieu. In higher animals this involve complex communication networks that link the brain and various metabolic centers. However, a comprehensive understanding of the processes involved in the maintenance of nutrient and energy homeostasis is still lacking, mainly due to the complex environmental changes and the intricate nature of the internal physiological response systems.

Our group focuses on the following aspects, which would enable us to understand better the mechanisms that maintain nutrient and energy homeostasis:​

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• Neural and endocrine signalling networks that maintain energy homeostasis.

• Cellular and systemic mechanisms that aid in nutrient sensing.

• Genetic regulation of developmental maturation, metabolism and ageing.

• Molecular mechanisms that maintain neural integrity and ageing. 

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