Publications from the lab
1. Fernandes, J., & Varghese, J. (2022). Sexually dimorphic microRNA miR-190 regulates lifespan in male Drosophila. RNA biology, 19(1), 1085-1093.
Read it here!
2. Fernandes, J*; Thomas, E*; Varghese, J (2022). Nutrient dependent miR-184 aids in the survival of Drosophila larvae during low food conditions. microPublication Biology, 10.17912/micropub.biology.000541.
Read it here!
3. Fernandes, J; Varghese, J (2022). A mini-screen to identify the role of microRNAs in the Drosophila Insulin-Producing cells regulating lifespan. microPublication Biology. 10.17912/micropub.biology.000536.
Read it here!
4. Pathak H, Varghese J. (2021). Edem1 activity in the fat body regulates insulin signalling and metabolic homeostasis in Drosophila. Life Science Alliance. 4(8):e202101079. doi: 10.26508/lsa.202101079.
Read it here!
5. Rehman N, Varghese J. (2021). Larval nutrition influences adult fat stores and starvation resistance in Drosophila. PLoS One. 16(2):e0247175. doi: 10.1371/journal.pone.0247175.
Read it here!
6. Pathak H*, Vijaykumar Maya A*, Tanari AB*, Sarkar S, Varghese J. (2021). Lint, a transmembrane serine protease, regulates growth and metabolism in Drosophila. Genetics. 218(1):iyab035. doi: 10.1093/genetics/iyab035.
Read it here!
7. Sudhakar SR, Pathak H, Rehman N, Fernandes J, Vishnu S, Varghese J. (2020). Insulin signalling elicits hunger-induced feeding in Drosophila. Developmental Biology. 459(2):87-99. doi:10.1016/j.ydbio.2019.11.013.
8. John A*, Vinayan K*, Varghese J. (2016). Achiasmy: Male Fruit Flies Are Not Ready to Mix. Frontiers in Cell and Developmental Biology. 4:75. doi: 10.3389/fcell.2016.00075.
Key publications of Dr. Jishy Varghese
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Varghese, J. Lim, S. F. and Cohen, S. M. (2010). Drosophila miR-14 regulates insulin production and metabolism through its target sugarbabe. Genes and Development 24(24):2748-53. (selected as the cover page of the journal)
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Varghese, J. and Cohen, S. M. (2007). microRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in Drosophila.Genes and Development. 21(18): 2277-82.
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Godbole, A., Varghese, J., Sarin, A and Mathew, M. K. (2003). VDAC is a conserved element of death pathways in plant and animal systems. Biochimica et Biophysica Acta – Molecular Cell Research 1642(1-2):87-96.
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Varghese, J*., Khandre, N. S* and Sarin, A (2003). Caspase-3 activation is an early event and initiates apoptotic damage in a human leukemia cell line. Apoptosis 8: 363- 370.
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Varghese, J., Sade, H., Vandenabeele, P and Sarin, A. (2002). Head involution defective (Hid)-triggered apoptosis requires caspase-8 but not FADD (Fas-associated death domain) and is regulated by Erk in mammalian cells. Journal of Biological Chemistry 277, 35097-104.
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Varghese, J., Radhika. G and Sarin, A. (2001). The role of calpain in caspase activation during etoposide induced apoptosis in T cells. European Journal of Immunology 31, 2035-41.
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Varghese, J., Chattopadhaya, S and Sarin, A. (2001). Inhibition of p38 Kinase Reveals a TNFalpha-Mediated, Caspase-Dependent, Apoptotic Death Pathway in a Human Myelomonocyte Cell Line. Journal of Immunology. 166, 6570-7.
*equal contribution
